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Guadalupe \gu(a)-dalu-pe, guad(a)-lupe\ as a girl's name is pronounced gwah-da-LOO-pay. It is of Spanish origin, and the meaning of Guadalupe is "wolf valley". Refers to Mary as Mexico's "Our Lady of Guadalupe". For more information, see also the related name Lupita. View a list of the 2 names that reference Guadalupe.

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